FDPS anticorps (C-Term)

N° du produit ABIN2774296

Cet anticorps anti-FDPS est un anticorps Lapin Polyclonal détectant FDPS dans WB et IHC. Adapté pour Humain, Rat, Souris, Chien, Cheval, Porc, Lapin, Boeuf (Vache) et Cobaye.

Aperçu rapide pour FDPS anticorps (C-Term) (ABIN2774296)

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Reactivité: Humain, Rat, Souris, Chien, Cheval, Porc, Lapin, Boeuf (Vache), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDPS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FDPS anticorps

Épitope: C-Term

Séquence: VKYKTAFYSF YLPIAAAMYM AGIDGEKEHA NAKKILLEMG EFFQIQDDYL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FDPS. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 353 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FDPS

Antigène: FDPS (Farnesyl Diphosphate Synthase (FDPS))

Autre désignation: FDPS

Sujet: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FPPS, FPS
Protein Interaction Partner: UBC, SUMO2, NME1, IDH1, ADSS, NME1-NME2, STAMBP, TALDO1, SORD, PLS3, EGFR, EIF4ENIF1, ATXN1, FGFR1,
Protein Size: 353

Poids moléculaire: 38 kDa

ID gène: 2224

NCBI Accession: NM_001135822, NP_001129294

UniProt: P14324

Pathways: Regulation of Muscle Cell Differentiation